Schematic Review Specialist Needed

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Hey folks, I'm working on a custom PCB for a thermoelectric cooler (TEC) controller as part of a biomedical device prototype. I'd love a sanity check on the circuit and general layout before I finalize the board. The system is designed to control the temperature of a medical probe using a TEC (model: RH14-14-10-L1-W4.5, max 3.9 A @ 1.7 V). The goal is to precisely control and monitor temperature in the range of 1°C–40°C using NTC thermistors and a STM32L476RG microcontroller. Core Features Power Input: Single 5 V, 5 A regulated supply Onboard LDO (TLV75533PDRVR) generates clean 3.3 V rail for digital/analog logic Microcontroller: STM32L476RG Thermistors: GA10K3MCD1 10kΩ NTC probes Used in voltage dividers with MCP4151 digital potentiometers to center Vout at VDD/2 at ~20.5 °C Signals buffered and amplified with OPA333, then sent to ADC Current Monitoring: 20 mΩ shunt resistor on TEC path Differential measurement via INA333, centered at VDD/2 for bidirectional current sensing TEC Control: DRV8876 H-bridge driver PWM input from STM32 (TIM1_CH1) modulates TEC power Direction pin configurable via GPIO I'm looking for feedback on: Analog signal integrity TEC power section Thermistor signal conditioning PCB layout best practices (GND plane, thermal via, etc.) Thanks in advance!

Keyword: Design layout

Price: $20.0

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